Elizabeth Borelli
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May 20, 2026

Recently, I found myself gathered around a table at a local pizza restaurant with a few new friends. The event organizer who brought us together had generously ordered dinner family-style, trying to accommodate everyone’s preferences, from vegan to gluten-free to “anything but pizza.” Two of us were fitness instructors, and everyone at the table would likely describe themselves as health-conscious.
You can learn a surprising amount about people over pizza.
One woman joked about her struggles to keep the weight on as she polished off her fourth piece of pizza, another claimed a single piece would tack on five pounds.
Exaggeration aside, the conversation highlighted something fascinating: we all process food differently.
Some people seem naturally lean no matter what they eat. Others feel like they gain weight just by looking at a plate of pasta. Beyond age and activity levels, our bodies appear to carry different metabolic and energy patterns, raising the question of how much genetics actually shape us, literally.
Years ago, we used to simplify our shapely differences into “somatypes”: ectomorph, mesomorph and endomorph. But modern science now recognizes that body composition is influenced by far more than inherited structure alone. Hormones, stress, sleep, gut health, trauma, inflammation, diet and activity levels all play a role.
And honestly, I find that encouraging. Because aside from age and genetics, many of those factors are surprisingly changeable.
Today, new research on gut health has introduced a more modern and scientifically nuanced way of thinking about body “types” known as phenotypes.
Gut phenotypes are essentially different “types” or patterns of gut microbiomes—the unique ecosystems of bacteria, fungi, and other microbes living in the digestive tract. Researchers use the term to describe how people’s guts function differently based on the composition of their microbiome, digestion, metabolism, and immune activity.
Just like at the pizza parlor, two people can eat the exact same meal, yet one feels energized while the other experiences bloating, fatigue, or blood sugar spikes. Part of that difference may come down to their gut phenotype.
Researchers are still refining the science, but some commonly discussed gut phenotypes include:
Today, phenotypes help us recognize that health is individualized, adaptive, and shaped by both biology and lifestyle. A decade ago, I believed I had to monitor my intake to be able to button my pants the next day. Today, all that has changed. I no longer pay attention to calories, I eat in a way that’s consistent with the Mediterranean approach to enjoy both delicious food and the health benefits it delivers. In short, I was able to let go of diet anxiety and finally enjoy food again.
The paradox is that highly regimented dietary patterns, like those found in complex carb-restricted diets or Weight Watcher-style eating plans, undermine gut health.
Instead, greater plant diversity and Mediterranean-style eating patterns are consistently associated with:
Which is also why the Mediterranean lifestyle works so well conceptually. Rather than forcing everyone into the same rigid plan, it supports healthier phenotypic expression through:
In many ways, phenotype thinking moves us away from labeling bodies and toward understanding systems.
The exciting part is that gut phenotypes are not fixed. Diet, stress, sleep, medications, movement and environment all influence the microbiome over time.
In Ayurveda, the three doshas—Vata, Pitta and Kapha—describe mind-body constitutions that influence digestion, energy, mood, metabolism and overall health. Modern researchers have started exploring whether these constitutional patterns might correlate with different gut microbiome profiles, or “gut phenotypes.”

Here’s the basic idea:
A few small studies from India have found measurable differences in gut bacteria composition among people classified into different dosha types. For example, certain bacterial strains appeared more abundant in specific Ayurvedic constitutions. But this research is still preliminary and far from conclusive.
What I find most interesting is the philosophical overlap.
Both Ayurveda and modern microbiome science recognize that:
And interestingly, many Ayurvedic principles overlap naturally with the Mediterranean lifestyle:
Modern science may be using the language of gut phenotypes and microbial diversity, while Ayurveda used the language of doshas thousands of years ago—but both point toward a similar truth: health is highly individualized, deeply interconnected and influenced by far more than calories alone.
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